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| Date | Matchup | Venue |
|---|---|---|
| @ Pittsburgh Pirates | LECOM Park | |
| vs Boston Red Sox | Charlotte Sports Park | |
| vs Minnesota Twins | Charlotte Sports Park | |
| @ Baltimore Orioles | Ed Smith Stadium | |
| @ Boston Red Sox | JetBlue Park | |
| vs Toronto Blue Jays | Charlotte Sports Park | |
| vs Detroit Tigers | Charlotte Sports Park | |
| @ Atlanta Braves | CoolToday Park | |
| @ Pittsburgh Pirates | LECOM Park | |
| @ Minnesota Twins | Lee Health Sports Complex | |
| vs Philadelphia Phillies | Charlotte Sports Park | |
| vs Kingdom of the Netherlands | Charlotte Sports Park | |
| vs Baltimore Orioles | Charlotte Sports Park | |
| @ New York Yankees | George M. Steinbrenner Field | |
| @ Boston Red Sox | JetBlue Park | |
| vs Atlanta Braves | Charlotte Sports Park | |
| @ Detroit Tigers | Publix Field at Joker Marchant Stadium | |
| vs Minnesota Twins | Charlotte Sports Park | |
| @ Atlanta Braves | CoolToday Park | |
| @ Boston Red Sox | JetBlue Park | |
| @ Minnesota Twins | Lee Health Sports Complex | |
| vs Pittsburgh Pirates | Charlotte Sports Park | |
| @ Atlanta Braves | CoolToday Park | |
| vs New York Yankees | Charlotte Sports Park | |
| @ Philadelphia Phillies | BayCare Ballpark | |
| vs Boston Red Sox | Charlotte Sports Park | |
| vs Minnesota Twins | Charlotte Sports Park | |
| @ Toronto Blue Jays | TD Ballpark | |
| @ Philadelphia Phillies | BayCare Ballpark | |
| @ Atlanta Braves | CoolToday Park | |
| @ St. Louis Cardinals | Busch Stadium | |
| @ St. Louis Cardinals | Busch Stadium | |
| @ St. Louis Cardinals | Busch Stadium | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| @ Minnesota Twins | Target Field | |
| @ Minnesota Twins | Target Field | |
| @ Minnesota Twins | Target Field | |
| vs Chicago Cubs | Tropicana Field | |
| vs Chicago Cubs | Tropicana Field | |
| vs Chicago Cubs | Tropicana Field | |
| vs New York Yankees | Tropicana Field | |
| vs New York Yankees | Tropicana Field | |
| vs New York Yankees | Tropicana Field | |
| @ Chicago White Sox | Rate Field | |
| @ Chicago White Sox | Rate Field | |
| @ Chicago White Sox | Rate Field | |
| @ Pittsburgh Pirates | PNC Park | |
| @ Pittsburgh Pirates | PNC Park | |
| @ Pittsburgh Pirates | PNC Park | |
| vs Cincinnati Reds | Tropicana Field | |
| vs Cincinnati Reds | Tropicana Field | |
| vs Cincinnati Reds | Tropicana Field | |
| vs Minnesota Twins | Tropicana Field | |
| vs Minnesota Twins | Tropicana Field | |
| vs Minnesota Twins | Tropicana Field | |
| @ Cleveland Guardians | Progressive Field | |
| @ Cleveland Guardians | Progressive Field | |
| @ Cleveland Guardians | Progressive Field | |
| vs San Francisco Giants | Tropicana Field | |
| vs San Francisco Giants | Tropicana Field | |
| vs San Francisco Giants | Tropicana Field | |
| vs Toronto Blue Jays | Tropicana Field | |
| vs Toronto Blue Jays | Tropicana Field | |
| vs Toronto Blue Jays | Tropicana Field | |
| @ Boston Red Sox | Fenway Park | |
| @ Boston Red Sox | Fenway Park | |
| @ Boston Red Sox | Fenway Park | |
| @ Boston Red Sox | Fenway Park | |
| @ Toronto Blue Jays | Rogers Centre | |
| @ Toronto Blue Jays | Rogers Centre | |
| @ Toronto Blue Jays | Rogers Centre | |
| vs Miami Marlins | Tropicana Field | |
| vs Miami Marlins | Tropicana Field | |
| vs Miami Marlins | Tropicana Field | |
| vs Baltimore Orioles | Tropicana Field | |
| vs Baltimore Orioles | Tropicana Field | |
| vs Baltimore Orioles | Tropicana Field | |
| @ New York Yankees | Yankee Stadium | |
| @ New York Yankees | Yankee Stadium | |
| @ New York Yankees | Yankee Stadium | |
| @ Baltimore Orioles | Oriole Park at Camden Yards | |
| @ Baltimore Orioles | Oriole Park at Camden Yards | |
| @ Baltimore Orioles | Oriole Park at Camden Yards | |
| vs Los Angeles Angels | Tropicana Field | |
| vs Los Angeles Angels | Tropicana Field | |
| vs Los Angeles Angels | Tropicana Field | |
| vs Detroit Tigers | Tropicana Field | |
| vs Detroit Tigers | Tropicana Field | |
| vs Detroit Tigers | Tropicana Field | |
| @ Miami Marlins | loanDepot park | |
| @ Miami Marlins | loanDepot park | |
| @ Miami Marlins | loanDepot park | |
| vs Boston Red Sox | Tropicana Field | |
| vs Boston Red Sox | Tropicana Field | |
| vs Boston Red Sox | Tropicana Field | |
| @ Los Angeles Angels | Angel Stadium | |
| @ Los Angeles Angels | Angel Stadium | |
| @ Los Angeles Angels | Angel Stadium | |
| @ Los Angeles Dodgers | Dodger Stadium | |
| @ Los Angeles Dodgers | Dodger Stadium | |
| @ Los Angeles Dodgers | Dodger Stadium | |
| vs Washington Nationals | Tropicana Field | |
| vs Washington Nationals | Tropicana Field | |
| vs Washington Nationals | Tropicana Field | |
| vs Kansas City Royals | Tropicana Field | |
| vs Kansas City Royals | Tropicana Field | |
| vs Kansas City Royals | Tropicana Field | |
| vs Kansas City Royals | Tropicana Field | |
| vs Arizona Diamondbacks | Tropicana Field | |
| vs Arizona Diamondbacks | Tropicana Field | |
| vs Arizona Diamondbacks | Tropicana Field | |
| @ Kansas City Royals | Kauffman Stadium | |
| @ Kansas City Royals | Kauffman Stadium | |
| @ Kansas City Royals | Kauffman Stadium | |
| @ Houston Astros | Daikin Park | |
| @ Houston Astros | Daikin Park | |
| @ Houston Astros | Daikin Park | |
| vs New York Yankees | Tropicana Field | |
| vs New York Yankees | Tropicana Field | |
| vs New York Yankees | Tropicana Field | |
| vs New York Yankees | Tropicana Field | |
| vs Seattle Mariners | Tropicana Field | |
| vs Seattle Mariners | Tropicana Field | |
| vs Seattle Mariners | Tropicana Field | |
| @ Boston Red Sox | Fenway Park | |
| @ Boston Red Sox | Fenway Park | |
| @ Boston Red Sox | Fenway Park | |
| @ Toronto Blue Jays | Rogers Centre | |
| @ Toronto Blue Jays | Rogers Centre | |
| @ Toronto Blue Jays | Rogers Centre | |
| @ Toronto Blue Jays | Rogers Centre | |
| vs Cleveland Guardians | Tropicana Field | |
| vs Cleveland Guardians | Tropicana Field | |
| vs Cleveland Guardians | Tropicana Field | |
| vs Texas Rangers | Tropicana Field | |
| vs Texas Rangers | Tropicana Field | |
| vs Texas Rangers | Tropicana Field | |
| vs Chicago White Sox | Tropicana Field | |
| vs Chicago White Sox | Tropicana Field | |
| vs Chicago White Sox | Tropicana Field | |
| @ Colorado Rockies | Coors Field | |
| @ Colorado Rockies | Coors Field | |
| @ Colorado Rockies | Coors Field | |
| @ Seattle Mariners | T-Mobile Park | |
| @ Seattle Mariners | T-Mobile Park | |
| @ Seattle Mariners | T-Mobile Park | |
| @ Athletics | Sutter Health Park | |
| @ Athletics | Sutter Health Park | |
| @ Athletics | Sutter Health Park | |
| vs Baltimore Orioles | Tropicana Field | |
| vs Baltimore Orioles | Tropicana Field | |
| vs Baltimore Orioles | Tropicana Field | |
| vs Baltimore Orioles | Tropicana Field | |
| vs Toronto Blue Jays | Tropicana Field | |
| vs Toronto Blue Jays | Tropicana Field | |
| vs Toronto Blue Jays | Tropicana Field | |
| @ Baltimore Orioles | Oriole Park at Camden Yards | |
| @ Baltimore Orioles | Oriole Park at Camden Yards | |
| @ Baltimore Orioles | Oriole Park at Camden Yards | |
| @ Detroit Tigers | Comerica Park | |
| @ Detroit Tigers | Comerica Park | |
| @ Detroit Tigers | Comerica Park | |
| vs San Diego Padres | Tropicana Field | |
| vs San Diego Padres | Tropicana Field | |
| vs San Diego Padres | Tropicana Field | |
| vs New York Mets | Tropicana Field | |
| vs New York Mets | Tropicana Field | |
| vs New York Mets | Tropicana Field | |
| @ Texas Rangers | Globe Life Field | |
| @ Texas Rangers | Globe Life Field | |
| @ Texas Rangers | Globe Life Field | |
| @ Texas Rangers | Globe Life Field | |
| @ Atlanta Braves | Truist Park | |
| @ Atlanta Braves | Truist Park | |
| @ Atlanta Braves | Truist Park | |
| vs Houston Astros | Tropicana Field | |
| vs Houston Astros | Tropicana Field | |
| vs Houston Astros | Tropicana Field | |
| vs Athletics | Tropicana Field | |
| vs Athletics | Tropicana Field | |
| vs Athletics | Tropicana Field | |
| vs Boston Red Sox | Tropicana Field | |
| vs Boston Red Sox | Tropicana Field | |
| vs Boston Red Sox | Tropicana Field | |
| @ New York Yankees | Yankee Stadium | |
| @ New York Yankees | Yankee Stadium | |
| @ New York Yankees | Yankee Stadium | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Philadelphia Phillies | Citizens Bank Park |