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| Date | Matchup | Venue |
|---|---|---|
| @ Detroit Pistons | Little Caesars Arena, Detroit, MI | |
| @ Toronto Raptors | Scotiabank Arena, Toronto, ON | |
| @ Brooklyn Nets | Barclays Center, Brooklyn, NY | |
| @ New York Knicks | Madison Square Garden, New York, NY | |
| @ Philadelphia 76ers | Xfinity Mobile Arena, Philadelphia, PA | |
| vs Detroit Pistons | Frost Bank Center, San Antonio, TX | |
| vs LA Clippers | Frost Bank Center, San Antonio, TX | |
| vs Houston Rockets | Frost Bank Center, San Antonio, TX | |
| vs Boston Celtics | Frost Bank Center, San Antonio, TX | |
| vs Denver Nuggets | Frost Bank Center, San Antonio, TX | |
| vs Charlotte Hornets | Frost Bank Center, San Antonio, TX | |
| @ LA Clippers | Intuit Dome, Inglewood, CA | |
| @ Sacramento Kings | Golden 1 Center, Sacramento, CA | |
| vs Phoenix Suns | Frost Bank Center, San Antonio, TX | |
| vs Indiana Pacers | Frost Bank Center, San Antonio, TX | |
| @ Miami Heat | Kaseya Center, Miami, FL | |
| @ Memphis Grizzlies | FedExForum, Memphis, TN | |
| @ Milwaukee Bucks | Fiserv Forum, Milwaukee, WI | |
| vs Chicago Bulls | Frost Bank Center, San Antonio, TX | |
| @ Golden State Warriors | Chase Center, San Francisco, CA | |
| @ LA Clippers | Intuit Dome, Inglewood, CA | |
| @ Denver Nuggets | Ball Arena, Denver, CO | |
| vs Philadelphia 76ers | Frost Bank Center, San Antonio, TX | |
| vs Portland Trail Blazers | Frost Bank Center, San Antonio, TX | |
| vs Dallas Mavericks | Frost Bank Center, San Antonio, TX | |
| vs Denver Nuggets | Frost Bank Center, San Antonio, TX |