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| Date | Matchup | Venue |
|---|---|---|
| @ Miami Marlins | loanDepot park | |
| @ Miami Marlins | loanDepot park | |
| @ Miami Marlins | loanDepot park | |
| vs Seattle Mariners | Busch Stadium | |
| vs Seattle Mariners | Busch Stadium | |
| vs Seattle Mariners | Busch Stadium | |
| @ Pittsburgh Pirates | PNC Park | |
| @ Pittsburgh Pirates | PNC Park | |
| @ Pittsburgh Pirates | PNC Park | |
| @ Pittsburgh Pirates | PNC Park | |
| vs Los Angeles Dodgers | Busch Stadium | |
| vs Los Angeles Dodgers | Busch Stadium | |
| vs Los Angeles Dodgers | Busch Stadium | |
| vs Milwaukee Brewers | Busch Stadium | |
| vs Milwaukee Brewers | Busch Stadium | |
| vs Milwaukee Brewers | Busch Stadium | |
| @ San Diego Padres | Petco Park | |
| @ San Diego Padres | Petco Park | |
| @ San Diego Padres | Petco Park | |
| @ San Diego Padres | Petco Park | |
| @ Athletics | Sutter Health Park | |
| @ Athletics | Sutter Health Park | |
| @ Athletics | Sutter Health Park | |
| vs Kansas City Royals | Busch Stadium | |
| vs Kansas City Royals | Busch Stadium | |
| vs Kansas City Royals | Busch Stadium | |
| vs Pittsburgh Pirates | Busch Stadium | |
| vs Pittsburgh Pirates | Busch Stadium | |
| vs Pittsburgh Pirates | Busch Stadium | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| vs Chicago Cubs | Busch Stadium | |
| vs Chicago Cubs | Busch Stadium | |
| vs Chicago Cubs | Busch Stadium | |
| vs Texas Rangers | Busch Stadium | |
| vs Texas Rangers Lou Gehrig Day | Busch Stadium | |
| vs Texas Rangers | Busch Stadium | |
| vs Cincinnati Reds | Busch Stadium | |
| vs Cincinnati Reds | Busch Stadium | |
| vs Cincinnati Reds | Busch Stadium | |
| @ New York Mets | Citi Field | |
| @ New York Mets | Citi Field | |
| @ New York Mets | Citi Field | |
| @ Minnesota Twins | Target Field | |
| @ Minnesota Twins | Target Field | |
| @ Minnesota Twins | Target Field | |
| vs San Diego Padres | Busch Stadium | |
| vs San Diego Padres | Busch Stadium | |
| vs San Diego Padres | Busch Stadium | |
| @ Kansas City Royals | Kauffman Stadium | |
| @ Kansas City Royals | Kauffman Stadium | |
| @ Kansas City Royals | Kauffman Stadium | |
| vs Arizona Diamondbacks | Busch Stadium | |
| vs Arizona Diamondbacks | Busch Stadium | |
| vs Arizona Diamondbacks | Busch Stadium | |
| vs Arizona Diamondbacks | Busch Stadium | |
| vs Miami Marlins | Busch Stadium | |
| vs Miami Marlins | Busch Stadium | |
| vs Miami Marlins | Busch Stadium | |
| @ Atlanta Braves | Truist Park | |
| @ Atlanta Braves | Truist Park | |
| @ Atlanta Braves | Truist Park | |
| @ Chicago Cubs | Wrigley Field | |
| @ Chicago Cubs | Wrigley Field | |
| @ Chicago Cubs | Wrigley Field | |
| vs Milwaukee Brewers | Busch Stadium | |
| vs Milwaukee Brewers | Busch Stadium | |
| vs Milwaukee Brewers | Busch Stadium | |
| vs Milwaukee Brewers | Busch Stadium | |
| vs Atlanta Braves | Busch Stadium | |
| vs Atlanta Braves | Busch Stadium | |
| vs Atlanta Braves | Busch Stadium | |
| @ Arizona Diamondbacks | Chase Field | |
| @ Arizona Diamondbacks | Chase Field | |
| @ Arizona Diamondbacks | Chase Field | |
| @ Los Angeles Angels | Angel Stadium | |
| @ Los Angeles Angels | Angel Stadium | |
| @ Los Angeles Angels | Angel Stadium | |
| vs Cincinnati Reds | Busch Stadium | |
| vs Cincinnati Reds | Busch Stadium | |
| vs Cincinnati Reds | Busch Stadium | |
| vs Chicago Cubs | Busch Stadium | |
| vs Chicago Cubs | Busch Stadium | |
| vs Chicago Cubs | Busch Stadium | |
| vs Chicago Cubs | Busch Stadium | |
| @ Toronto Blue Jays | Rogers Centre | |
| @ Toronto Blue Jays | Rogers Centre | |
| @ Toronto Blue Jays | Rogers Centre | |
| @ New York Yankees | Yankee Stadium | |
| @ New York Yankees | Yankee Stadium | |
| @ New York Yankees | Yankee Stadium | |
| vs Colorado Rockies | Busch Stadium | |
| vs Colorado Rockies | Busch Stadium | |
| vs Colorado Rockies | Busch Stadium | |
| vs Philadelphia Phillies | Busch Stadium | |
| vs Philadelphia Phillies | Busch Stadium | |
| vs Philadelphia Phillies | Busch Stadium | |
| @ Chicago Cubs | Wrigley Field | |
| @ Chicago Cubs | Wrigley Field | |
| @ Chicago Cubs | Wrigley Field | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| vs Baltimore Orioles | Busch Stadium | |
| vs Baltimore Orioles | Busch Stadium | |
| vs Baltimore Orioles | Busch Stadium | |
| vs Pittsburgh Pirates | Busch Stadium | |
| vs Pittsburgh Pirates | Busch Stadium | |
| vs Pittsburgh Pirates | Busch Stadium | |
| @ Los Angeles Dodgers | UNIQLO Field at Dodger Stadium | |
| @ Los Angeles Dodgers | UNIQLO Field at Dodger Stadium | |
| @ Los Angeles Dodgers | UNIQLO Field at Dodger Stadium | |
| @ Colorado Rockies | Coors Field | |
| @ Colorado Rockies | Coors Field | |
| @ Colorado Rockies | Coors Field | |
| @ San Francisco Giants | Oracle Park | |
| @ San Francisco Giants | Oracle Park | |
| @ San Francisco Giants | Oracle Park | |
| vs Chicago White Sox | Busch Stadium | |
| vs Chicago White Sox | Busch Stadium | |
| vs Chicago White Sox | Busch Stadium | |
| vs San Francisco Giants | Busch Stadium | |
| vs San Francisco Giants Roberto Clemente Day | Busch Stadium | |
| vs San Francisco Giants | Busch Stadium | |
| vs Washington Nationals | Busch Stadium | |
| vs Washington Nationals | Busch Stadium | |
| vs Washington Nationals | Busch Stadium | |
| @ Pittsburgh Pirates | PNC Park | |
| @ Pittsburgh Pirates | PNC Park | |
| @ Pittsburgh Pirates | PNC Park | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |