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| Date | Matchup | Venue |
|---|---|---|
| @ Colorado Rockies | Coors Field | |
| @ Colorado Rockies | Coors Field | |
| vs Seattle Mariners | PNC Park | |
| vs Seattle Mariners | PNC Park | |
| vs Seattle Mariners | PNC Park | |
| vs Cincinnati Reds | PNC Park | |
| vs Cincinnati Reds | PNC Park | |
| vs Cincinnati Reds | PNC Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Washington Nationals | Nationals Park | |
| @ Washington Nationals | Nationals Park | |
| @ Washington Nationals | Nationals Park | |
| vs Atlanta Braves | PNC Park | |
| vs Atlanta Braves | PNC Park | |
| vs Atlanta Braves | PNC Park | |
| vs Milwaukee Brewers | PNC Park | |
| vs Milwaukee Brewers | PNC Park | |
| vs Milwaukee Brewers | PNC Park | |
| @ Cleveland Guardians | Progressive Field | |
| @ Cleveland Guardians | Progressive Field | |
| @ Cleveland Guardians | Progressive Field | |
| @ New York Yankees | Yankee Stadium | |
| @ New York Yankees | Yankee Stadium | |
| @ New York Yankees | Yankee Stadium | |
| vs Chicago Cubs | PNC Park | |
| vs Chicago Cubs | PNC Park | |
| vs Chicago Cubs | PNC Park | |
| vs Arizona Diamondbacks | PNC Park | |
| vs Arizona Diamondbacks | PNC Park | |
| vs Arizona Diamondbacks | PNC Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| vs New York Mets | PNC Park | |
| vs New York Mets | PNC Park | |
| vs New York Mets | PNC Park | |
| @ Miami Marlins | loanDepot park | |
| @ Miami Marlins | loanDepot park | |
| @ Miami Marlins | loanDepot park | |
| vs Boston Red Sox | PNC Park | |
| vs Boston Red Sox | PNC Park | |
| vs Boston Red Sox | PNC Park | |
| vs Detroit Tigers | PNC Park | |
| vs Detroit Tigers | PNC Park | |
| vs Detroit Tigers | PNC Park | |
| @ Los Angeles Dodgers | UNIQLO Field at Dodger Stadium | |
| @ Los Angeles Dodgers | UNIQLO Field at Dodger Stadium | |
| @ Los Angeles Dodgers | UNIQLO Field at Dodger Stadium | |
| @ San Diego Padres | Petco Park | |
| @ San Diego Padres | Petco Park | |
| @ San Diego Padres | Petco Park | |
| @ St. Louis Cardinals | Busch Stadium | |
| @ St. Louis Cardinals | Busch Stadium | |
| @ St. Louis Cardinals | Busch Stadium | |
| vs San Francisco Giants | PNC Park | |
| vs San Francisco Giants | PNC Park | |
| vs San Francisco Giants | PNC Park | |
| vs Los Angeles Angels | PNC Park | |
| vs Los Angeles Angels | PNC Park | |
| vs Los Angeles Angels | PNC Park | |
| @ Chicago White Sox | Rate Field | |
| @ Chicago White Sox | Rate Field | |
| @ Chicago White Sox | Rate Field | |
| @ Chicago Cubs | Wrigley Field | |
| @ Chicago Cubs | Wrigley Field | |
| @ Chicago Cubs | Wrigley Field | |
| vs Milwaukee Brewers Roberto Clemente Day | PNC Park | |
| vs Milwaukee Brewers | PNC Park | |
| vs Milwaukee Brewers | PNC Park | |
| vs Kansas City Royals | PNC Park | |
| vs Kansas City Royals | PNC Park | |
| vs Kansas City Royals | PNC Park | |
| vs St. Louis Cardinals | PNC Park | |
| vs St. Louis Cardinals | PNC Park | |
| vs St. Louis Cardinals | PNC Park | |
| @ Detroit Tigers | Comerica Park | |
| @ Detroit Tigers | Comerica Park | |
| @ Detroit Tigers | Comerica Park |