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| Date | Matchup | Venue |
|---|---|---|
| vs Tampa Bay Rays | LECOM Park | |
| @ Philadelphia Phillies | BayCare Ballpark | |
| vs New York Yankees | LECOM Park | |
| @ Boston Red Sox | JetBlue Park | |
| @ Atlanta Braves | CoolToday Park | |
| vs Minnesota Twins | LECOM Park | |
| vs Baltimore Orioles | LECOM Park | |
| @ Houston Astros | CACTI Park of the Palm Beaches | |
| @ St. Louis Cardinals | Roger Dean Chevrolet Stadium | |
| vs Tampa Bay Rays | LECOM Park | |
| vs Colombia | LECOM Park | |
| vs St. Louis Cardinals | LECOM Park | |
| vs Philadelphia Phillies | LECOM Park | |
| @ Toronto Blue Jays | TD Ballpark | |
| @ Detroit Tigers | Publix Field at Joker Marchant Stadium | |
| vs Boston Red Sox | LECOM Park | |
| @ New York Yankees | George M. Steinbrenner Field | |
| @ Baltimore Orioles | Ed Smith Stadium | |
| vs Atlanta Braves | LECOM Park | |
| @ Detroit Tigers | Publix Field at Joker Marchant Stadium | |
| vs Baltimore Orioles | LECOM Park | |
| @ Tampa Bay Rays | Charlotte Sports Park | |
| @ Minnesota Twins | Lee Health Sports Complex | |
| vs Houston Astros | LECOM Park | |
| vs Detroit Tigers | LECOM Park | |
| @ Baltimore Orioles | Ed Smith Stadium | |
| @ Atlanta Braves | CoolToday Park | |
| vs Toronto Blue Jays | LECOM Park | |
| vs Boston Red Sox | LECOM Park | |
| vs Atlanta Braves | LECOM Park | |
| @ New York Mets | Citi Field | |
| @ New York Mets | Citi Field | |
| @ New York Mets | Citi Field | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| vs Baltimore Orioles | PNC Park | |
| vs Baltimore Orioles | PNC Park | |
| vs Baltimore Orioles | PNC Park | |
| vs San Diego Padres | PNC Park | |
| vs San Diego Padres | PNC Park | |
| vs San Diego Padres | PNC Park | |
| @ Chicago Cubs | Wrigley Field | |
| @ Chicago Cubs | Wrigley Field | |
| @ Chicago Cubs | Wrigley Field | |
| vs Washington Nationals | PNC Park | |
| vs Washington Nationals | PNC Park | |
| vs Washington Nationals | PNC Park | |
| vs Washington Nationals | PNC Park | |
| vs Tampa Bay Rays | PNC Park | |
| vs Tampa Bay Rays | PNC Park | |
| vs Tampa Bay Rays | PNC Park | |
| @ Texas Rangers | Globe Life Field | |
| @ Texas Rangers | Globe Life Field | |
| @ Texas Rangers | Globe Life Field | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| vs St. Louis Cardinals | PNC Park | |
| vs St. Louis Cardinals | PNC Park | |
| vs St. Louis Cardinals | PNC Park | |
| vs St. Louis Cardinals | PNC Park | |
| vs Cincinnati Reds | PNC Park | |
| vs Cincinnati Reds | PNC Park | |
| vs Cincinnati Reds | PNC Park | |
| @ Arizona Diamondbacks | Chase Field | |
| @ Arizona Diamondbacks | Chase Field | |
| @ Arizona Diamondbacks | Chase Field | |
| @ San Francisco Giants | Oracle Park | |
| @ San Francisco Giants | Oracle Park | |
| @ San Francisco Giants | Oracle Park | |
| vs Colorado Rockies | PNC Park | |
| vs Colorado Rockies | PNC Park | |
| vs Colorado Rockies | PNC Park | |
| vs Philadelphia Phillies | PNC Park | |
| vs Philadelphia Phillies | PNC Park | |
| vs Philadelphia Phillies | PNC Park | |
| @ St. Louis Cardinals | Busch Stadium | |
| @ St. Louis Cardinals | Busch Stadium | |
| @ St. Louis Cardinals | Busch Stadium | |
| @ Toronto Blue Jays | Rogers Centre | |
| @ Toronto Blue Jays | Rogers Centre | |
| @ Toronto Blue Jays | Rogers Centre | |
| vs Chicago Cubs | PNC Park | |
| vs Chicago Cubs | PNC Park | |
| vs Chicago Cubs | PNC Park | |
| vs Chicago Cubs | PNC Park | |
| vs Minnesota Twins | PNC Park | |
| vs Minnesota Twins | PNC Park | |
| vs Minnesota Twins | PNC Park | |
| @ Houston Astros | Daikin Park | |
| @ Houston Astros | Daikin Park | |
| @ Houston Astros | Daikin Park | |
| @ Atlanta Braves | Truist Park | |
| @ Atlanta Braves | Truist Park | |
| @ Atlanta Braves | Truist Park | |
| vs Los Angeles Dodgers | PNC Park | |
| vs Los Angeles Dodgers | PNC Park | |
| vs Los Angeles Dodgers | PNC Park | |
| vs Miami Marlins | PNC Park | |
| vs Miami Marlins | PNC Park | |
| vs Miami Marlins | PNC Park | |
| @ Athletics | Sutter Health Park | |
| @ Athletics | Sutter Health Park | |
| @ Athletics | Sutter Health Park | |
| @ Colorado Rockies | Coors Field | |
| @ Colorado Rockies | Coors Field | |
| @ Colorado Rockies | Coors Field | |
| vs Seattle Mariners | PNC Park | |
| vs Seattle Mariners | PNC Park | |
| vs Seattle Mariners | PNC Park | |
| vs Cincinnati Reds | PNC Park | |
| vs Cincinnati Reds | PNC Park | |
| vs Cincinnati Reds | PNC Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Philadelphia Phillies | Citizens Bank Park | |
| @ Washington Nationals | Nationals Park | |
| @ Washington Nationals | Nationals Park | |
| @ Washington Nationals | Nationals Park | |
| vs Atlanta Braves | PNC Park | |
| vs Atlanta Braves | PNC Park | |
| vs Atlanta Braves | PNC Park | |
| vs Milwaukee Brewers | PNC Park | |
| vs Milwaukee Brewers | PNC Park | |
| vs Milwaukee Brewers | PNC Park | |
| @ Cleveland Guardians | Progressive Field | |
| @ Cleveland Guardians | Progressive Field | |
| @ Cleveland Guardians | Progressive Field | |
| @ New York Yankees | Yankee Stadium | |
| @ New York Yankees | Yankee Stadium | |
| @ New York Yankees | Yankee Stadium | |
| vs Chicago Cubs | PNC Park | |
| vs Chicago Cubs | PNC Park | |
| vs Chicago Cubs | PNC Park | |
| vs Arizona Diamondbacks | PNC Park | |
| vs Arizona Diamondbacks | PNC Park | |
| vs Arizona Diamondbacks | PNC Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Cincinnati Reds | Great American Ball Park | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| @ Milwaukee Brewers | American Family Field | |
| vs New York Mets | PNC Park | |
| vs New York Mets | PNC Park | |
| vs New York Mets | PNC Park | |
| @ Miami Marlins | loanDepot park | |
| @ Miami Marlins | loanDepot park | |
| @ Miami Marlins | loanDepot park | |
| vs Boston Red Sox | PNC Park | |
| vs Boston Red Sox | PNC Park | |
| vs Boston Red Sox | PNC Park | |
| vs Detroit Tigers | PNC Park | |
| vs Detroit Tigers | PNC Park | |
| vs Detroit Tigers | PNC Park | |
| @ Los Angeles Dodgers | Dodger Stadium | |
| @ Los Angeles Dodgers | Dodger Stadium | |
| @ Los Angeles Dodgers | Dodger Stadium | |
| @ San Diego Padres | Petco Park | |
| @ San Diego Padres | Petco Park | |
| @ San Diego Padres | Petco Park | |
| @ St. Louis Cardinals | Busch Stadium | |
| @ St. Louis Cardinals | Busch Stadium | |
| @ St. Louis Cardinals | Busch Stadium | |
| vs San Francisco Giants | PNC Park | |
| vs San Francisco Giants | PNC Park | |
| vs San Francisco Giants | PNC Park | |
| vs Los Angeles Angels | PNC Park | |
| vs Los Angeles Angels | PNC Park | |
| vs Los Angeles Angels | PNC Park | |
| @ Chicago White Sox | Rate Field | |
| @ Chicago White Sox | Rate Field | |
| @ Chicago White Sox | Rate Field | |
| @ Chicago Cubs | Wrigley Field | |
| @ Chicago Cubs | Wrigley Field | |
| @ Chicago Cubs | Wrigley Field | |
| vs Milwaukee Brewers | PNC Park | |
| vs Milwaukee Brewers | PNC Park | |
| vs Milwaukee Brewers | PNC Park | |
| vs Kansas City Royals | PNC Park | |
| vs Kansas City Royals | PNC Park | |
| vs Kansas City Royals | PNC Park | |
| vs St. Louis Cardinals | PNC Park | |
| vs St. Louis Cardinals | PNC Park | |
| vs St. Louis Cardinals | PNC Park | |
| @ Detroit Tigers | Comerica Park | |
| @ Detroit Tigers | Comerica Park | |
| @ Detroit Tigers | Comerica Park |