| Aug 16 | vs West Ham United | Turf Moor, BurnleyCBSSN, Paramount+ |
| Aug 23 | @ West Bromwich Albion | The Hawthorns, West BromwichParamount+ |
| Aug 29 | @ Norwich City | Carrow Road, NorwichParamount+ |
| Sep 2 | vs Middlesbrough | Turf Moor, BurnleyParamount+ |
| Sep 5 | vs Bristol City | Turf Moor, BurnleyParamount+ |
| Sep 8 | @ Wrexham | STōK Cae Ras, WrexhamParamount+ |
| Sep 12 | @ Swansea City | Swansea.com Stadium, SwanseaParamount+ |
| Sep 19 | vs Derby County | Turf Moor, BurnleyParamount+ |
| Oct 10 | @ Watford | Vicarage Road, WatfordParamount+ |
| Oct 13 | vs Charlton Athletic | Turf Moor, Burnley |
| Oct 16 | vs Wolverhampton Wanderers | Turf Moor, BurnleyParamount+ |
| Oct 24 | @ Lincoln City | LNER Stadium, LincolnParamount+ |
| Oct 31 | vs Portsmouth | Turf Moor, Burnley |
| Nov 3 | @ Queens Park Rangers | MATRADE Loftus Road, LondonParamount+ |
| When | Matchup | Venue and broadcast |
|---|---|---|
| Nov 7 | @ Cardiff City | Cardiff City Stadium, Cardiff |
| Nov 22 | vs Blackburn Rovers | Turf Moor, BurnleyParamount+ |
| Nov 25 | vs Birmingham City | Turf Moor, Burnley |
| Nov 28 | @ Millwall | The Den, London |
| Dec 6 | vs Preston North End | Turf Moor, Burnley |
| Dec 9 | @ Southampton | St. Mary's Stadium, Southampton |
| Dec 12 | @ Sheffield United | Bramall Lane, Sheffield |
| Dec 19 | vs Stoke City | Turf Moor, Burnley |
| Dec 26 | @ Bolton Wanderers | Toughsheet Community Stadium, Bolton |
| Dec 29 | vs Lincoln City | Turf Moor, Burnley |
| Jan 1 | vs Sheffield United | Turf Moor, Burnley |
| Jan 16 | @ Wolverhampton Wanderers | Molineux Stadium, Wolverhampton |
| Jan 23 | @ Portsmouth | Fratton Park, Portsmouth |
| Jan 26 | vs Queens Park Rangers | Turf Moor, Burnley |
| Jan 30 | vs Cardiff City | Turf Moor, Burnley |
| Feb 6 | @ Blackburn Rovers | Ewood Park, Blackburn |
| Feb 13 | vs Swansea City | Turf Moor, Burnley |
| Feb 16 | @ Charlton Athletic | The Valley, London |
| Feb 20 | @ Derby County | Pride Park, Derby |
| Feb 27 | vs Watford | Turf Moor, Burnley |
| Mar 2 | vs West Bromwich Albion | Turf Moor, Burnley |
| Mar 6 | @ West Ham United | London Stadium, London |
| Mar 13 | vs Millwall | Turf Moor, Burnley |
| Mar 16 | @ Preston North End | Deepdale, Preston |
| Mar 20 | vs Bolton Wanderers | Turf Moor, Burnley |
| Apr 3 | @ Stoke City | bet365 Stadium, Stoke-on-Trent |
| Apr 6 | vs Wrexham | Turf Moor, Burnley |
| Apr 10 | @ Bristol City | Ashton Gate, Bristol |
| Apr 17 | vs Norwich City | Turf Moor, Burnley |
| Apr 20 | @ Middlesbrough | Riverside Stadium, Middlesbrough |
| Apr 24 | vs Southampton | Turf Moor, Burnley |
| May 1 | @ Birmingham City | St. Andrew's Stadium, Birmingham |